PD 325901

Drug Profile

PD 325901

Alternative Names: PD-0325901; PD-325901

Latest Information Update: 28 Sep 2017

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At a glance

  • Originator Pfizer
  • Developer BIOENSIS; Pfizer; SpringWorks Therapeutics; University of Alabama at Birmingham; University of Oxford
  • Class Aniline compounds; Antineoplastics; Benzamides; Small molecules
  • Mechanism of Action MAP kinase kinase 1 inhibitors; MAP kinase kinase 2 inhibitors; Mitogen-activated protein kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Neurofibromatoses
  • Phase I Colorectal cancer
  • Preclinical Cervical cancer
  • Discontinued Breast cancer; Cancer; Malignant melanoma; Non-small cell lung cancer

Most Recent Events

  • 25 Sep 2017 SpringWorks Therapeutics, a Pfizer spinoff, is developing PD 325901
  • 25 Sep 2017 SpringWorks plans a phase III trial program for Neurofibromatosis
  • 01 Apr 2017 Preclinical trials in Cervical cancer (Combination therapy) in USA
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