Technetium Tc99m etarfolatide

Drug Profile

Technetium Tc99m etarfolatide

Alternative Names: 99mTC-Etarfolatide; EC 145 companion diagnostic - Endocyte; EC-20; Etarfolatide; Etarfolatide TC99m; Folate-Tc99m; FolateScan; FOLCEPRI; In 111-EC20; NMK 20; Tc 99m-EC20; Vintafolide companion diagnostic

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Endocyte
  • Developer Endocyte; Nihon Medi-Physics
  • Class Imaging agents; Radiopharmaceutical diagnostics
  • Mechanism of Action Single-photon emission-computed tomography enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Ovarian cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-small cell lung cancer; Pituitary cancer; Renal cell carcinoma
  • Preregistration Submission Withdrawal Ovarian cancer
  • No development reported Solid tumours
  • Discontinued Inflammation

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for phase-I development in Solid-tumours(In volunteers) in Japan (IV, Injection)
  • 28 Aug 2015 Development of technetium etarfolatide is still ongoing for Pituitary cancer and Renal cell carcinoma (Diagnosis) in USA (Endocyte pipeline, August 2015)
  • 31 Mar 2015 Technetium Tc99m etarfolatide is still in phase II trials for Non-small cell lung cancer (Diagnosis) in USA and Europe
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