Research programme: phosphatidylinositol 3-kinase inhibitors - Roche

Drug Profile

Research programme: phosphatidylinositol 3-kinase inhibitors - Roche

Alternative Names: PI 509; PI 516; PI-540; PI-620; RO2492

Latest Information Update: 07 Mar 2011

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At a glance

  • Originator Astellas Pharma; Cancer Research UK; Ludwig Institute for Cancer Research; The Institute of Cancer Research
  • Developer Roche
  • Class Small molecules
  • Mechanism of Action 1 Phosphatidylinositol 3 kinase inhibitors; Phosphatidylinositol 3 kinase delta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Preclinical Haematological malignancies; Rheumatoid arthritis
  • Discontinued Viral infections

Most Recent Events

  • 07 Mar 2011 Preclinical development is ongoing in United Kingdom
  • 27 May 2008 Piramed has been acquired and merged into Roche
  • 16 Apr 2008 Pharmacodynamics data from a preclinical trial in Cancer presented at the 99th Annual Meeting of the American Association for Cancer Research (AACR-2008)
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