Drug Profile


Alternative Names: BIIB 067; ISIS 333611; ISIS-SOD1Rx; SODr/h333611

Latest Information Update: 27 Apr 2017

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At a glance

  • Originator Center for Neurologic Study; Isis Pharmaceuticals; Ludwig Institute for Cancer Research
  • Developer Ionis Pharmaceuticals
  • Class Antisense oligonucleotides
  • Mechanism of Action Superoxide dismutase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyotrophic lateral sclerosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Amyotrophic lateral sclerosis

Most Recent Events

  • 08 Mar 2017 Biogen and Ionis Pharmaceutical initiates a phase I extension trial in Amyotrophic lateral sclerosis in USA, Canada, Belgium, Germany and United Kingdom (NCT03070119)
  • 07 Mar 2017 Biogen plans a phase I trial for Amyotrophic lateral sclerosis (NCT03070119)
  • 18 Dec 2015 Isis Pharmaceuticals is now called Ionis Pharmaceuticals
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