Drug Profile


Alternative Names: CS-3543; CX-3543; Itarnafloxin

Latest Information Update: 11 Mar 2013

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At a glance

  • Originator Cylene Pharmaceuticals
  • Class Antineoplastics; Fluoroquinolones; Small molecules
  • Mechanism of Action Apoptosis stimulants; RNA synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Chronic lymphocytic leukaemia; Neuroendocrine tumours

Most Recent Events

  • 06 Mar 2013 Quarfloxin licensed to TetraGene
  • 30 Jun 2010 Discontinued - Phase-II for Neuroendocrine tumours in USA (IV)
  • 03 Nov 2008 Discontinued - Phase-II for Chronic lymphocytic leukaemia in USA (IV)
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