Drug Profile


Alternative Names: Anti-TNF-alpha monoclonal antibody - Centocor/Medarex; CNTO-148; Shinponi; Simponi; Simponi Aria; Simponi I.V; Sympony; Symposony

Latest Information Update: 21 Jul 2017

$50 / €47 *
* $ price applies to USA, Canada and Latin America. € price applies to the rest of the world. Final gross prices may vary according to local VAT.

At a glance

  • Originator Centocor; Medarex
  • Developer Centocor; Centocor Ortho Biotech; Janssen Biotech; Janssen Pharmaceutical KK; Merck & Co; Mitsubishi Tanabe Pharma Corporation
  • Class Anti-inflammatories; Anti-TNF monoclonal antibodies; Antirheumatics
  • Mechanism of Action Immunomodulators; Tumour necrosis factor alpha inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Sarcoidosis
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Ankylosing spondylitis; Juvenile rheumatoid arthritis; Psoriatic arthritis; Rheumatoid arthritis; Ulcerative colitis
  • Phase I/II Hearing disorders
  • Phase I Type 1 diabetes mellitus
  • Discontinued Asthma; Cardiovascular disorders; Sarcoidosis; Uveitis

Most Recent Events

  • 04 Jul 2017 Launched for Juvenile rheumatoid arthritis (Combination therapy) in Norway (SC)
  • 14 Jun 2017 Additional efficacy data from a the phase III GO-ALIVE trial in Ankylosing spondylitis presented at the 18th Annual Congress of the European League Against Rheumatism (EULAR-2017)
  • 14 Jun 2017 Safety and efficacy data from the phase III GO-VIBRANT trial in Psoriatic arthritis released by Janssen
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