MM 111

Drug Profile

MM 111

Alternative Names: MM-111

Latest Information Update: 04 Dec 2015

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At a glance

  • Originator Merrimack Pharmaceuticals
  • Class Antineoplastics; Bispecific antibodies; Recombinant fusion proteins
  • Mechanism of Action ERBB 2 receptor antagonists; ERBB-3 receptor antagonists; Neuregulin-1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Gastric cancer; Oesophageal cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Breast cancer; Gastric cancer; Oesophageal cancer; Solid tumours

Most Recent Events

  • 26 Feb 2015 9175306 - Merrimack stops enrolment in phase II trial
  • 26 Feb 2015 Discontinued - Phase-I for Breast cancer (Combination therapy, Late-stage disease, Recurrent, Second-line therapy or greater) in USA (IV)
  • 26 Feb 2015 Discontinued - Phase-I for Solid tumours (Late-stage disease) in USA (IV)
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