Sobetirome

Drug Profile

Sobetirome

Alternative Names: GC-1; NV 1205; QRX-431

Latest Information Update: 24 Jul 2017

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At a glance

  • Originator University of California at San Francisco
  • Developer NeuroVia; QuatRx Pharmaceuticals; University of California at San Francisco
  • Class Acetic acids; Antihyperlipidaemics; Benzhydryl compounds; Obesity therapies; Phenols; Small molecules
  • Mechanism of Action Thyroid hormone receptor beta agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Adrenoleucodystrophy
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Adrenoleucodystrophy
  • Discontinued Lipid metabolism disorders; Obesity

Most Recent Events

  • 20 Jul 2017 Pharmacodynamics data from a preclinical trial in Adrenoleucodystrphy released by NeuroVia
  • 05 May 2017 NeuroVia plans a phase I/II trial for Adrenoleukodystrophy (X-linked, In children, In adolescents) in Australia (PO) in October 2017 (NCT03196765)
  • 29 Apr 2011 Sobetirome receives Orphan Drug status for Adrenoleucodystrophy in USA
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