Rigosertib

Drug Profile

Rigosertib

Alternative Names: Estybon; Novonex; ON-01910; ON-01910-sodium; ON-01910.Na; Rigosertib sodium; SyB C-1101; SyB L-1101; SyB-1101

Latest Information Update: 14 Jun 2017

Price : $50

At a glance

  • Originator Onconova Therapeutics
  • Developer Onconova Therapeutics; SymBio Pharmaceuticals
  • Class Amino acids; Antineoplastics; Small molecules; Sulfones
  • Mechanism of Action 1 Phosphatidylinositol 3 kinase inhibitors; Polo-like kinase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer; Myelodysplastic syndromes
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Chronic myelomonocytic leukaemia; Myelodysplastic syndromes
  • Phase II Acute myeloid leukaemia; Solid tumours
  • Phase I Head and neck cancer
  • No development reported Acute lymphoblastic leukaemia; Chronic lymphocytic leukaemia; Ovarian cancer; Pancreatic cancer
  • Discontinued Squamous cell cancer

Most Recent Events

  • 05 Jun 2017 Efficacy data from a phase II trial in Myelodysplastic syndrome presented at the 53rd Annual Meeting of the American Society of Clinical Oncology (ASCO-2017)
  • 15 May 2017 Onconova in collaboration with National Institutes of Health and National Cancer Institute plans clinical trial in Cancer
  • 31 Mar 2017 Onconova files a clinical trial application for the phase III INSPIRE trial for Myelodysplastic syndrome in Estonia, Hungary and Russia
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