Drug Profile


Alternative Names: Ala-glu-asp-gly - BioDiem; Alanyl glutamyl aspartyl glycine - BioDiem; BDM-E; Epitalon - BioDiem; Epitalon tetrapeptide - BioDiem; Epithalon - BioDiem; Epithalon tetrapeptide - BioDiem

Latest Information Update: 15 Dec 2016

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At a glance

  • Originator Institute of Bioregulation and Gerontology
  • Developer BioDiem; Monash University; University of Cambridge; University of Wisconsin at Milwaukee
  • Class Eye disorder therapies; Oligopeptides; Small molecules
  • Mechanism of Action Angiogenesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Retinitis pigmentosa
  • New Molecular Entity Yes
  • Available For Licensing Yes - Retinitis pigmentosa

Highest Development Phases

  • Phase I/II Diabetic macular oedema
  • Preclinical Age-related macular degeneration; Retinitis pigmentosa; Retinopathy of prematurity

Most Recent Events

  • 23 Sep 2015 BioDiem is still seeking licensees to enable the continued development of BDM E for Retinal diseases
  • 08 Apr 2011 Genzyme Corporation has been acquired by sanofi-aventis
  • 09 Sep 2010 BDM E is available for licensing in USA for Retinitis pigmentosa as of 09 Sep 2010.
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