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Avacincaptad pegol - IVERIC bio

Drug Profile

Avacincaptad pegol - IVERIC bio

Alternative Names: Anti-C5 aptamer; ARC-1905; Avacincaptad pegol sodium; IZERVAY; Zimura

Latest Information Update: 24 Mar 2024

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At a glance

  • Originator Archemix Corporation
  • Developer IVERIC bio
  • Class Eye disorder therapies; Oligonucleotides; Polyethylene glycols
  • Mechanism of Action Complement C5 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Dry age-related macular degeneration
  • Phase III Stargardt disease
  • Phase II Polypoidal choroidal vasculopathy; Wet age-related macular degeneration

Most Recent Events

  • 24 Mar 2024 Phase-III clinical trials in Stargardt disease (unspecified route), prior to March 2024 (Iveric Bio pipeline, March 2024)
  • 04 Nov 2023 Efficacy and adverse events data from the phase III GATHER2 trial in geographic atrophy (GA) secondary to Dry age-related macular degeneration released by IVERIC bio
  • 18 Sep 2023 Efficacy and adverse events data from phase-III GATHER2 trial in Dry age-related macular degeneration released by Iveric Bio
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