Avacincaptad pegol

Drug Profile

Avacincaptad pegol

Alternative Names: Anti-C5 aptamer; ARC-187; ARC-1905; Avacincaptad pegol sodium

Latest Information Update: 02 Jun 2016

Price : $50

At a glance

  • Originator Archemix Corporation
  • Developer OphthoTech Corporation
  • Class Eye disorder therapies; Oligonucleotides; Polyethylene glycols
  • Mechanism of Action Complement C5 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Dry age-related macular degeneration
  • Phase II Wet age-related macular degeneration

Most Recent Events

  • 27 Jan 2016 Phase-II/III clinical trials in Dry age-related macular degeneration in USA (Intravitreous) (NCT02686658)
  • 27 Jan 2016 Ophthotech Corporation initiates enrolment in a phase II clinical trials in Wet age-related macular degeneration (Combination therapy) in USA (Intravitreous)
  • 22 Sep 2015 A phase II/III trial in Dry age-related macular degeneration is still planned for late 2015
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