Avacincaptad pegol

Drug Profile

Avacincaptad pegol

Alternative Names: Anti-C5 aptamer; ARC-187; ARC-1905; Avacincaptad pegol sodium; Zimura

Latest Information Update: 15 Nov 2017

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At a glance

  • Originator Archemix Corporation
  • Developer OphthoTech Corporation
  • Class Eye disorder therapies; Oligonucleotides; Polyethylene glycols
  • Mechanism of Action Complement C5 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Dry age-related macular degeneration
  • Phase II Wet age-related macular degeneration

Most Recent Events

  • 08 Nov 2017 Ophthotech reported submitting the revised protocol for its phase II study in Dry macular generation to the US FDA in early Q4 2017
  • 19 Sep 2017 Opthotech initiates a phase IIa trial in Wet age-related macular degeneration (Combination therapy) in Unknown locations (Intravitreous)
  • 26 Jul 2017 Ophthotech plans a clinical trial for Wet age-related macular degeneration (Combination therapy) in unknown countries by the end of 2017
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