Research programme: nitric oxide-donating therapies for eye disorders - NicOx

Drug Profile

Research programme: nitric oxide-donating therapies for eye disorders - NicOx

Alternative Names: NCX 1021; NCX 1653; NCX 422; NCX 434; NCX 470; NCX 667

Latest Information Update: 12 Oct 2017

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At a glance

  • Originator NicOx
  • Class Nitroso compounds; Pregnadienetriols
  • Mechanism of Action Nitric oxide donors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Diabetic macular oedema; Diabetic retinopathy; Glaucoma; Ocular hypertension

Most Recent Events

  • 11 Oct 2017 Nicox and pSivida enter into a collaboration agreement to develop sustained release formulations of nitric oxide donating compounds for Ocular hypertension and Glaucoma
  • 21 Feb 2017 Pharmacodynamics data from preclinical studies in Glaucoma and Ocular hypertension released by Nicox
  • 24 Jan 2017 NicOx announces intention to submit IND for NCX 470 to US FDA in Q4 2017
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