Research programme: nitric oxide-donating therapies for eye disorders - NicOx

Drug Profile

Research programme: nitric oxide-donating therapies for eye disorders - NicOx

Alternative Names: NCX 1021; NCX 1653; NCX 422; NCX 434; NCX 470; NCX 667

Latest Information Update: 06 Jan 2017

Price : $50

At a glance

  • Originator NicOx
  • Class Nitroso compounds; Pregnadienetriols
  • Mechanism of Action Nitric oxide donors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Diabetic macular oedema; Diabetic retinopathy; Glaucoma; Ocular hypertension

Most Recent Events

  • 05 Jan 2017 NicOx plans phase II trials of NCX 470 for Glaucoma
  • 03 Jun 2015 Preclinical trials in Ocular hypertension in France (Ophthalmic) before June 2015
  • 05 Aug 2010 Research programme available for licensing worldwide (
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