Drug Profile


Alternative Names: DEB-025; DEBIO-025; DEBIO-25

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Debiopharm
  • Developer Debiopharm; Solid Biosciences
  • Class Ciclosporins
  • Mechanism of Action Cyclophilin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Hepatitis C
  • Preclinical Duchenne muscular dystrophy

Most Recent Events

  • 01 Apr 2016 Novartis terminates phase III trial in Hepatitis C (combination therapy, treatment-naive African American patients) in USA (NCT01446250)
  • 08 Sep 2015 Debiopharm International and Solid Biosciences collaborated to co-develop alisporivir for Duchenne muscular dystrophy
  • 08 Sep 2015 Preclinical trials in Duchenne muscular dystrophy in USA (PO)
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