Drug Profile


Alternative Names: Esmirtazapine maleate; ORG-50081; SCH 900265

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Organon
  • Developer Merck & Co
  • Class Dibenzazepines; Sleep disorder therapies; Small molecules
  • Mechanism of Action Serotonin 2A receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Insomnia; Vasomotor symptoms

Most Recent Events

  • 01 Mar 2010 Discontinued - Phase-III for Insomnia in Canada (PO)
  • 01 Mar 2010 Discontinued - Phase-III for Insomnia in USA (PO)
  • 01 Mar 2010 Discontinued - Phase-III for Vasomotor symptoms in Australia (PO)
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