Research programme: ubiquitin ligase inhibitors - Proteologics

Drug Profile

Research programme: ubiquitin ligase inhibitors - Proteologics

Alternative Names: Midline-1 inhibitor - Proteologics; PRT14-2; PRT3; PRT42; PRT44; TRIM 18 inhibitor - Proteologics

Latest Information Update: 21 Mar 2013

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At a glance

  • Originator Proteologics
  • Developer GlaxoSmithKline; Proteologics; University of Newcastle, Australia
  • Class Small molecules
  • Mechanism of Action HIV replication inhibitors; Ubiquitin-protein ligase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Asthma; Cancer
  • Discontinued HIV infections

Most Recent Events

  • 18 Mar 2013 Ubiquitin ligase inhibitors is still in preclinical trials for Cancer is Israel
  • 01 Mar 2013 Ubiquitin ligase inhibitors programme is available for licensing as of 01 Mar 2013.
  • 25 Feb 2013 Discontinued - Preclinical for HIV infections in Israel (unspecified route)
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