Drug Profile
Research programme: gamma secretase inhibitors - Merck
Alternative Names: MRK-003; MRK-560Latest Information Update: 04 Nov 2017
Price :
$50
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At a glance
- Originator Merck & Co
- Class Benzodiazepines; Small molecules; Sulfonamides; Sulfones
- Mechanism of Action Amyloid precursor protein secretase inhibitors; Notch signalling pathway inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- No development reported Alzheimer's disease; Cancer
Most Recent Events
- 04 Nov 2017 No recent reports of development identified for preclinical development in Alzheimer's-disease in USA (PO)
- 04 Nov 2017 No recent reports of development identified for preclinical development in Cancer in USA (PO)
- 16 Apr 2008 Pharmacodynamics and adverse events data from a preclinical trial in Cancer presented at the 99th Annual Meeting of the American Association for Cancer Research (AACR-2008)