423557

Drug Profile

423557

Alternative Names: NPSP790; SB-423557

Latest Information Update: 24 Feb 2015

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At a glance

  • Originator NPS Pharmaceuticals
  • Developer Shire
  • Class Osteoporosis therapies; Small molecules
  • Mechanism of Action Calcium-sensing receptor antagonists; Osteogenesis stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Hypocalcaemia
  • Discontinued Osteoporosis

Most Recent Events

  • 21 Feb 2015 NPS Pharmaceuticals has been acquired by Shire
  • 03 Aug 2011 423557 is no longer licensed to GlaxoSmithKline worldwide
  • 03 Aug 2011 Phase-I clinical trials in autosomal dominant Hypocalcaemia with hypercalciuria (in volunteers) in USA (PO)
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