R-phenserine

Drug Profile

R-phenserine

Alternative Names: (+)-(3aR)-phenserine; (+)-phenserine; Posiphen

Latest Information Update: 17 Mar 2017

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At a glance

  • Originator National Institute on Aging; National Institutes of Health (USA); Raptor Pharmaceutical Corp
  • Developer Cenomed BioSciences; QR Pharma; Rockefeller University; University of California at Los Angeles
  • Class Nootropics; Phenylcarbamates; Small molecules
  • Mechanism of Action Acetylcholinesterase inhibitors; Alpha-synuclein inhibitors; Amyloid beta-protein precursor inhibitors; HD protein inhibitors; Tau protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Alzheimer's disease; Mild cognitive impairment; Parkinson's disease
  • Preclinical Brain injuries; Huntington's disease; Poisoning

Most Recent Events

  • 16 Mar 2017 Pharmacodynamics data from a preclinical trial in Alzheimer's disease and Parkinson's disease released by QR Pharma
  • 02 Mar 2017 Phase-I/II clinical trials in Alzheimer's disease (In adults, In the elderly) in USA (PO) (NCT02925650)
  • 15 Dec 2016 Biomarkers information updated
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