Drug Profile


Alternative Names: CS-3150; XL-550

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Exelixis
  • Developer Daiichi Sankyo Company
  • Class Antihyperglycaemics; Antihypertensives; Pyrroles; Small molecules; Sulfones
  • Mechanism of Action Mineralocorticoid receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Essential hypertension; Hyperaldosteronism; Hypertension
  • Phase II Diabetic nephropathies
  • No development reported Cardiovascular disorders; Heart failure

Most Recent Events

  • 08 Sep 2017 Daiichi Sankyo Company plans a phase III trial for Type-2 diabetes (with Microalbuminuria) in Japan (JapicCTI-173695)
  • 29 Aug 2017 Daiichi Sankyo Company completes the phase I pharmacokinetics trial in Japan (PO) (JapicCTI-163339)
  • 01 Aug 2017 Daiichi Sankyo completes a phase III trial in Hypertension (in patients with moderate renal impairment) (Combination therapy) in Japan (JapicCTI-163288)
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