Chlormethine

Drug Profile

Chlormethine

Alternative Names: Clearazide™; Ledaga; Mechlorethamine gel; Nitrogen mustard topical gel; Topical nitrogen mustard; Valchlor

Latest Information Update: 25 Mar 2017

Price : $50

At a glance

  • Originator Yaupon Therapeutics
  • Developer Actelion Pharmaceuticals
  • Class Antineoplastics; Nitrogen mustard compounds; Small molecules
  • Mechanism of Action Alkylating agents; T-cell receptor gene inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cutaneous T cell lymphoma
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Mycosis fungoides

Most Recent Events

  • 07 Mar 2017 Registered for Mycosis fungoides in Liechtenstein, Iceland, Norway, European Union (Topical)
  • 07 Mar 2017 Additional efficacy and adverse events data from a phase II trial in Mycosis fungoides released by Actelion
  • 16 Dec 2016 CHMP recommends approval of chlormethine for Mycosis fungoides in European Union (Topical)
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top