Research programme: antibody directed enzyme prodrug therapy - Genencor

Drug Profile

Research programme: antibody directed enzyme prodrug therapy - Genencor

Alternative Names: GCR-8886/2141

Latest Information Update: 14 Mar 2008

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At a glance

  • Originator Genencor International
  • Class Amidohydrolases; Antibodies; Recombinant fusion proteins
  • Mechanism of Action Alkylating agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Cancer

Most Recent Events

  • 13 Jun 2005 Genencor International has been acquired by Danisco A/S
  • 23 Mar 2005 Genencor has filed an IND with the FDA in USA for colorectal and pancreatic cancer
  • 07 Dec 2004 A preclinical study has been added to the Cancer pharmacodynamics section
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