ELND 005

Drug Profile

ELND 005

Alternative Names: AZD-103; ELND-005; Quercinitol; Scyllitol; Scyllo-inositol; Scyllocyclohexanehexol

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Transition Therapeutics
  • Developer Speranza Therapeutics; Transition Therapeutics
  • Class Antidementias; Cyclohexanols; Nootropics; Small molecules
  • Mechanism of Action Amyloid beta-protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Alzheimer's disease
  • Phase II Cognition disorders; Down syndrome
  • Discontinued Bipolar disorders

Most Recent Events

  • 31 Aug 2016 Transition Therapeutics has been acquired by OPKO Health
  • 15 Oct 2015 Efficacy and safety data from the phase II/III HARMONY AD trial released by Transition Therapeutics
  • 07 Jul 2015 Elan Pharmaceuticals terminates a phase II extension trial for Alzheimer's disease (for treatment of agitation and aggression) (In adults, In the elderly) in USA, Canada, Spain and United Kingdom (NCT01766336)
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