Drug Profile


Alternative Names: AIDS-222089; Bedaquiline fumarate; R 403323; R-207910; Sirturo; TMC-207; TMC207 oral solution

Latest Information Update: 25 Mar 2017

Price : $50

At a glance

  • Originator Johnson & Johnson
  • Developer Global Alliance for TB Drug Development; Janssen Infectious Diseases BVBA
  • Class Antituberculars; Dimethylamines; Naphthalenes; Quinolines; Small molecules
  • Mechanism of Action Adenosine triphosphatase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Tuberculosis
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Tuberculosis

Most Recent Events

  • 13 Feb 2017 Adverse events and efficacy data from a phase I trial in Tuberculosis presented at the 24th Conference on Retroviruses and Opportunistic Infections
  • 01 May 2016 Janssen Research and Development initiates enrolment in a phase II trial for Multi-drug resistant tuberculosis (Combination therapy, In children, In adolescents) in South Africa, Russia, Philippines (NCT02354014)
  • 21 Mar 2016 Launched for Tuberculosis (Combination therapy) in India (PO)
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