Drug Profile


Alternative Names: P-1446A-05; P1446

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Piramal Life Sciences
  • Developer Dana-Farber Cancer Institute; MEI Pharma; Norris Cotton Cancer Center; Piramal Enterprises
  • Class Small molecules
  • Mechanism of Action Cyclin-dependent kinase 4 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Chronic lymphocytic leukaemia; Malignant melanoma
  • Preclinical Diffuse large B cell lymphoma
  • No development reported Cancer

Most Recent Events

  • 05 Sep 2017 Voruciclib licensed to MEI Pharma worldwide
  • 03 Dec 2016 Presage biosciences plans a phase Ib trial for relapsed/refractory Diffuse large B cell lymphoma (Combination therapy) in USA
  • 03 Dec 2016 Preclinical trials in Diffuse large B cell lymphoma in USA (PO)
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