Drug Profile


Alternative Names: BIM-28131; BIM-28163; RM 131

Latest Information Update: 17 Oct 2017

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At a glance

  • Originator Ipsen
  • Developer Allergan; Ipsen
  • Class Gastrokinetics; Growth hormone-releasing hormones; Peptides; Piperidines; Thiophenes
  • Mechanism of Action Ghrelin receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Diabetic gastroparesis
  • Phase II Constipation; Gastrointestinal disorders
  • Discontinued Cachexia

Most Recent Events

  • 29 Sep 2017 Phase-III clinical trials in Diabetic gastroparesis in USA (SC) (NCT03285308)
  • 02 Nov 2016 Efficacy data from a phase IIb trial in Diabetic gastroparesis released by Allergan
  • 27 Oct 2016 Allergan exercises its option to acquire Motus, and plans to complete the acquisition by the end of 2016
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