Drug Profile


Alternative Names: BAY 1192631; DA-70157; DA-70218; DA-7157; DA-7218; MK-1986; SIVEXTRO; Tedizolid phosphate; Torezolid; Torezolid phosphate; TR-700; TR-701; TR-701 FA; TR-701 free acid

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Dong-A Pharmaceutical
  • Developer Bayer; Dong-A ST; Merck & Co
  • Class Antibacterials; Oxazolidinones; Small molecules
  • Mechanism of Action Ribosomal protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Skin and soft tissue infections
  • Phase III Nosocomial pneumonia
  • Phase I Bacteraemia; Gram-positive infections

Most Recent Events

  • 12 Jul 2017 Merck, Sharp and Dohme plans the phase I MK-1986-014 trial for Gram-positive infections (In neonates, In infants, Treatment-experienced) (PO) (IV) (NCT03217565)
  • 05 Jun 2017 Phase-III clinical trials in Skin and soft tissue infections (In children, In infants) in USA (PO) (EudraCT2016-003884-20)
  • 05 Jun 2017 Phase-III clinical trials in Skin and soft tissue infections (In infants, In children) in USA (IV) (EudraCT2016-003884-20)
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