Drug Profile


Alternative Names: GC-33; RG 7686; RO 5137382

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Perseus Proteomics
  • Developer Chugai Pharmaceutical; Roche
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Glypican 3 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Hepatocellular carcinoma

Most Recent Events

  • 01 Aug 2016 Chugai initiates enrolment in a phase I trial for Hepatocellular carcinoma (Combination therapy, Late-stage disease, Metastatic disease) in Taiwan (IV) (JapicCTI163325)
  • 01 Aug 2016 Phase-I clinical trials in Hepatocellular carcinoma (Combination therapy, Late-stage disease, Metastatic disease) in Japan (IV) (JapicCTI163325)
  • 12 Sep 2015 Phase II development of GC 33 is ongoing
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