Drug Profile


Alternative Names: FosD; Fostamatinib disodium; Fostamatinib sodium; R 985788; R-406/788; R-788; R-935/788; R788 sodium; R935788 sodium; Tamatinib fosdium

Latest Information Update: 25 Mar 2017

Price : $50

At a glance

  • Originator Rigel Pharmaceuticals
  • Developer AstraZeneca; Duke University Medical Center; Rigel Pharmaceuticals
  • Class Anti-inflammatories; Antianaemics; Antirheumatics; Oxazines; Phosphoric acid esters; Pyridines; Pyrimidines; Small molecules
  • Mechanism of Action B cell inhibitors; Syk kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Immune thrombocytopenic purpura
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Immune thrombocytopenic purpura
  • Phase II Autoimmune haemolytic anaemia; IgA nephropathy
  • Phase I Graft-versus-host disease
  • Discontinued Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Rheumatoid arthritis; Solid tumours; Systemic lupus erythematosus; T cell lymphoma; Type 1 diabetes mellitus

Most Recent Events

  • 07 Mar 2017 Efficacy data from the FIT phase III trials , 048 and 049 studies) for Immune thrombocytopenic purpura released by Rigel Pharmaceuticals
  • 30 Jan 2017 Efficacy data from phase III Study 049 in Immune thrombocytopenic purpura released by Rigel Pharmaceuticals
  • 30 Jan 2017 Pooled efficacy data from phase III Study 047 and 048 in Immune thrombocytopenic purpura released by Rigel Pharmaceuticals
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