Drug Profile


Alternative Names: Adnectin™ BMS-844203; Angiocept; BMS-844203; CT-322

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Adnexus Therapeutics
  • Developer Adnexus Therapeutics; Bristol-Myers Squibb
  • Class Antineoplastics; Fibronectins
  • Mechanism of Action Vascular endothelial growth factor receptor-2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Colorectal cancer; Glioblastoma; Non-Hodgkin's lymphoma; Non-small cell lung cancer

Most Recent Events

  • 15 Dec 2016 Biomarkers information updated
  • 23 Oct 2013 Discontinued - Phase-I for Glioblastoma (combination therapy, first-line therapy, newly diagnosed) in USA (IV)
  • 23 Oct 2013 Discontinued - Phase-II for Colorectal cancer (combination therapy, metastatic disease, second-line therapy or greater) in the USA, Argentina and Italy (IV)
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