Drug Profile


Alternative Names: N-Desmethylclozapine; ACP-104

Latest Information Update: 18 Jun 2008

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At a glance

  • Originator ACADIA Pharmaceuticals
  • Class Antipsychotics; Dibenzazepines; Nootropics; Small molecules
  • Mechanism of Action Dopamine D2 receptor agonists; Dopamine D3 receptor agonists; Muscarinic M1 receptor agonists; Serotonin 2A receptor inverse agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Schizophrenia

Most Recent Events

  • 16 Jun 2008 Discontinued - Phase-II for Schizophrenia in USA (PO)
  • 16 Jun 2008 Interim efficacy data from a phase IIb trial in Schizophrenia released by ACADIA Pharmaceuticals
  • 15 Dec 2007 ACADIA Pharmaceuticals completes enrolment in its phase IIb trial for Schziophrenia in the US
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