Dociparstat sodium

Drug Profile

Dociparstat sodium

Alternative Names: CX-01; ODSH; PGX-100; PGX-ODSH-2013-AML-1

Latest Information Update: 27 Apr 2017

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At a glance

  • Originator ParinGenix
  • Developer Cantex Pharmaceuticals
  • Class Anti-inflammatories; Antineoplastics; Heparins; Ischaemic heart disorder therapies; Polysaccharides
  • Mechanism of Action Cathepsin G inhibitors; HMGB1 protein inhibitors; Leucocyte elastase inhibitors; P selectin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Acute myeloid leukaemia; Myelodysplastic syndromes; Pancreatic cancer
  • Phase I Brain injuries
  • Clinical Phase Unknown Lung cancer; Solid tumours
  • Discontinued Acute coronary syndromes; Chronic obstructive pulmonary disease; Myocardial infarction; Reperfusion injury; Thrombocytopenia

Most Recent Events

  • 19 Apr 2017 Phase-II clinical trials in Myelodysplastic syndromes in USA (IV)
  • 07 Apr 2017 Phase-I clinical trials in Acute myeloid leukaemia (Combination therapy, Second-line therapy or greater) in USA (IV) (NCT02995655)
  • 07 Apr 2017 Phase-I clinical trials in Myelodysplastic syndromes (Combination therapy, Second-line therapy or greater) in USA (IV) (NCT02995655)
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