AIR 645

Drug Profile

AIR 645

Alternative Names: AIR645; ISIS-369645

Latest Information Update: 28 Mar 2012

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At a glance

  • Originator Isis Pharmaceuticals
  • Developer Altair Therapeutics
  • Class Anti-inflammatories; Antiasthmatics; Antisense oligonucleotides; Oligonucleotides
  • Mechanism of Action Interleukin 13 inhibitors; Interleukin 4 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Allergic asthma; Asthma; Rhinitis

Most Recent Events

  • 31 Dec 2010 Isis Pharmaceuticals reacquires AIR 645 and related assets from Altair Therapeutics
  • 31 Dec 2010 Discontinued - Phase-I for Asthma in Canada (Inhalation)
  • 31 Dec 2010 Discontinued - Phase-II for Allergic asthma in Canada (Inhalation)
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