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Nadofaragene firadenovec - FKD Therapies

Drug Profile

Nadofaragene firadenovec - FKD Therapies

Alternative Names: AAV-IFN-apha-2b-gene-therapy-FKD-Therapies; Adenovirus-Delivered Interferon Alpha-2b; Adstiladrin; FE-999326; Instiladrin; Nadofaragene firadenovec-vncg; Nadofaragene firadenovec/Syn3; rAd-IFNα; rAd-IFNα/Syn3; SCH-209702/SCH-721015; SCH-721015; SCH-721015/SCH-209702; TR-002

Latest Information Update: 14 Mar 2024

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At a glance

  • Originator Schering-Plough
  • Developer Ferring Pharmaceuticals; FKD Therapies; Trizell; University of Pennsylvania
  • Class Antineoplastics; IFNA2B gene therapies; Immunotherapies
  • Mechanism of Action Gene transference; IFNA2B expression stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Bladder cancer
  • Phase III Malignant-mesothelioma

Most Recent Events

  • 25 Jan 2024 Efficacy data from a phase II trial in Bladder cancer presented at the 2024 Genitourinary Cancers Symposium (ASCO-GeCS-2024)
  • 29 Nov 2023 Updated efficacy data from a phase III LANDMARK trial in Bladder cancer released by Ferring Pharmaceuticals
  • 12 Sep 2023 Launched for Bladder cancer (Late-stage disease, Second-line therapy or greater, In adults) in USA (Intravesicular)
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