Drug Profile


Alternative Names: Monomethylauristatin E-antiPSMA monoclonal antibody conjugate; PSMA Antibody Drug Conjugate

Latest Information Update: 25 Apr 2017

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At a glance

  • Originator Progenics Pharmaceuticals; PSMA Development Company
  • Developer Brown University; Progenics Pharmaceuticals; Rhode Island Hospital; University of Texas at Dallas
  • Class Antineoplastics; Auristatins; Drug conjugates; Immunotoxins; Monoclonal antibodies
  • Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Glioblastoma; Prostate cancer

Most Recent Events

  • 09 Mar 2017 Progenics Pharmaceuticals has patent protection for PSMA ADC in USA and Europe
  • 09 Mar 2017 Progenics Pharmaceuticals has patents pending for PSMA ADC in USA
  • 21 Jun 2016 Progenics Pharmaceuticals in-licenses CHO-M Cell Line and SUREtechnology platform from Selexis
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