Drug Profile


Alternative Names: Monomethylauristatin E-antiPSMA monoclonal antibody conjugate; prostate specific membrane antigen antibody-drug conjugate; PSMA Antibody Drug Conjugate

Latest Information Update: 04 Jul 2016

Price : $50

At a glance

  • Originator Progenics Pharmaceuticals; PSMA Development Company
  • Developer Brown University; Progenics Pharmaceuticals; Rhode Island Hospital; University of Texas at Dallas
  • Class Antineoplastics; Auristatins; Drug conjugates; Immunotoxins; Monoclonal antibodies
  • Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Glioblastoma; Prostate cancer

Most Recent Events

  • 21 Jun 2016 Progenics Pharmaceuticals in-licenses CHO-M Cell Line and SUREtechnology platform from Selexis
  • 15 Mar 2016 Biomarkers information updated
  • 23 Jun 2015 Phase-II development is ongoing in the US
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