Abexinostat

Drug Profile

Abexinostat

Alternative Names: CG-781; CRA-024781; PCI-24781; S 78454

Latest Information Update: 05 Jun 2017

Price : $50

At a glance

  • Originator Celera Genomics Group
  • Developer GlaxoSmithKline; Massachusetts General Hospital; Pharmacyclics; Servier; University of California at San Francisco
  • Class Amides; Antineoplastics; Benzofurans; Dimethylamines; Hydroxamic acids; Phenyl ethers; Small molecules
  • Mechanism of Action Histone deacetylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Chronic lymphocytic leukaemia; Follicular lymphoma; Lymphoma; Mantle-cell lymphoma
  • Phase I/II Sarcoma
  • Phase I Acute lymphoblastic leukaemia; Acute myeloid leukaemia; Breast cancer; Myelodysplastic syndromes; Nasopharyngeal cancer; Ovarian cancer; Solid tumours

Most Recent Events

  • 22 May 2017 Xynomic Pharmaceuticals plans a phase II/III PAX trial for Renal cancer
  • 22 May 2017 Xynomic Pharmaceuticals plans registrational phase III trials in Haematological malignancies in 2H 2017
  • 22 Apr 2017 Efficacy data from a phase Ib trial in Solid tumours released by Xynomic Pharmaceuticals
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