Raltegravir

Drug Profile

Raltegravir

Alternative Names: Isentress; ISENTRESS HD; L 900612; MK-0518

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Merck & Co
  • Developer Merck & Co; National Institute of Allergy and Infectious Diseases; The French National Agency for Research on AIDS and Viral Hepatitis
  • Class Antiretrovirals; Naphthyridines; Organic chemicals; Small molecules
  • Mechanism of Action HIV integrase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - HIV-1 infections
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed HIV-1 infections

Most Recent Events

  • 24 Jul 2017 Safety and efficacy data from the phase III ONCEMRK trial in HIV-1 infection released by Merck
  • 13 Jul 2017 Registered for HIV-1 infections (Combination therapy, Treatment-naive, Treatment-experienced) in Iceland, Liechtenstein, Norway, European Union (PO)
  • 30 May 2017 Adverse events and efficacy data from a phase III trial in HIV-1 infections released by Merck
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