Drug Profile


Alternative Names: Isentress; ISENTRESS HD; L 900612; MK-0518

Latest Information Update: 11 Jul 2017

Price : $50

At a glance

  • Originator Merck & Co
  • Developer Merck & Co; National Institute of Allergy and Infectious Diseases; The French National Agency for Research on AIDS and Viral Hepatitis
  • Class Antiretrovirals; Naphthyridines; Organic chemicals; Small molecules
  • Mechanism of Action HIV integrase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - HIV-1 infections
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed HIV-1 infections

Most Recent Events

  • 30 May 2017 Adverse events and efficacy data from a phase III trial in HIV-1 infections released by Merck
  • 26 May 2017 Registered for HIV-1 infections (Combination therapy, Treatment-naive, Treatment-experienced) in USA (PO, 1200mg once daily)
  • 19 May 2017 Committee for Medicinal Products for Human Use recommends approval of raltegravir for HIV-1 infections (Combination therapy, Treatment-naive, Treatment-experienced) in European Union (PO, 1200mg once daily)
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