Drug Profile


Alternative Names: ARRY-334543; ARRY-543; ASLAN-001; QBT01; SPS4370; Varlitinib tosylate

Latest Information Update: 10 Mar 2017

Price : $50

At a glance

  • Originator Array BioPharma
  • Developer Array BioPharma; ASLAN Pharmaceuticals
  • Class Antineoplastics; Quinazolines; Small molecules
  • Mechanism of Action Epidermal growth factor receptor antagonists; ERBB 2 receptor antagonists; ERBB 4 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cholangiocarcinoma; Biliary cancer; Gastric cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Biliary cancer
  • Phase II Breast cancer; Cholangiocarcinoma; Gastric cancer
  • Phase I Solid tumours

Most Recent Events

  • 28 Apr 2017 Aslan Pharmaceuticals plans a phase II trial for Biliary cancer(Metastatic disease, Late-stage disease, First-line therapy, Inoperable/unresectable, Combination therapy) (NCT03129074)
  • 28 Apr 2017 Aslan Pharmaceuticals plans a phase II/III trial for Gastric cancer (First-line therapy, Combination therapy, Metastatic disease, Late-stage disease) (NCT03130790)
  • 31 Mar 2017 Aslan Pharmaceuticals plans the TreeTopp phase II/III trial for Biliary cancer(Combination therapy, Metastatic disease, Late-stage disease, Second-line therapy, Inoperable/unresectable) in USA (NCT03093870)
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