Apatinib

Drug Profile

Apatinib

Alternative Names: Apatinib mesylate; YN-968-D1

Latest Information Update: 07 Dec 2016

Price : $50

At a glance

  • Originator Advenchen Laboratories LLC
  • Developer Bukwang Pharmaceutical; Fudan University Shanghai Cancer Center; Jiangsu Hengrui Medicine Co.; LSK Biopharma
  • Class Amides; Antineoplastics; Small molecules
  • Mechanism of Action Angiogenesis inhibitors; Proto oncogene protein c ret inhibitors; Vascular endothelial growth factor receptor-2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Gastric cancer
  • Phase III Hepatocellular carcinoma; Non-small cell lung cancer
  • Phase II Breast cancer; Colorectal cancer; Solid tumours

Most Recent Events

  • 26 Jul 2016 LSK BioPharma plans a pivotal phase III trial for Gastric cancer in USA, European Union, Japan, Korea and Taiwan
  • 20 Jul 2016 Phase-II clinical trials in Solid tumours in South Korea, USA (PO) (Advenchen Laboratories pipeline, July 2016)
  • 01 Jul 2016 Jiangsu HengRui Medicine Co. initiates a phase I pharmacokinetics trial in Healthy volunteers in China (PO, Tablet) (NCT02836171)
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