Research programme: farnesoid X receptor modulators - Phenex/Gilead Sciences

Drug Profile

Research programme: farnesoid X receptor modulators - Phenex/Gilead Sciences

Latest Information Update: 09 Jan 2015

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At a glance

  • Originator Phenex Pharmaceuticals
  • Class Small molecules
  • Mechanism of Action Farnesoid X-activated receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Metabolic syndrome; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis

Most Recent Events

  • 05 Jan 2015 Gilead Sciences and Phenex Pharmaceuticals enter into an agreement for Gilead to acquire Phenex's FXR programme of small molecule FXR agonists for the treatment of liver disorders, including non-alcoholic steatohepatitis (NASH)
  • 01 Oct 2013 This programme is still in active development
  • 13 Dec 2005 Preclinical trials in Primary sclerosing cholangitis in Germany (unspecified route)
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