Research programme: bone morphogenetic protein activators - Curis

Drug Profile

Research programme: bone morphogenetic protein activators - Curis

Alternative Names: BMP activators; BMP agonists; BMP-7 protein; eptotermin alfa analogues; eptotermin alfa mimetics

Latest Information Update: 19 Jan 2011

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At a glance

  • Originator Curis
  • Class Small molecules
  • Mechanism of Action Bone morphogenetic protein activators; Intercellular signalling peptide and protein stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Kidney disorders; Neurological disorders; Vascular disorders

Most Recent Events

  • 22 May 2007 This research programme is available for licensing worldwide (
  • 19 May 2007 Ortho Biotech Products terminates its worldwide licence to this research programme
  • 12 Dec 2005 Curis and Centocor expanded their collaboration agreement to screen and validate small molecule agonists based on Curis' BMP technology portfolio
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