Drug Profile


Alternative Names: KF 89617; LY 2523355

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Kyowa Hakko
  • Developer Eli Lilly; Kyowa Hakko
  • Class Amides; Antineoplastics; Small molecules; Thiadiazoles
  • Mechanism of Action KIF11 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Breast cancer; Colorectal cancer; Gastric cancer; Head and neck cancer; Leukaemia; Non-small cell lung cancer; Oesophageal cancer; Ovarian cancer; Prostate cancer; Small cell lung cancer; Solid tumours

Most Recent Events

  • 26 Apr 2013 Discontinued - Phase-I for Leukaemia (acute leukaemia) in USA (IV)
  • 26 Apr 2013 Discontinued - Phase-I for Solid tumours (late-stage disease, metastatic disease) in Japan (IV)
  • 26 Apr 2013 Discontinued - Phase-II for Breast cancer (metastatic disease) in USA (IV)
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