EVT 101

Drug Profile

EVT 101

Alternative Names: ENS 101; EVT101

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Roche
  • Developer Evotec AG
  • Class Antidementias; Antiparkinsonians
  • Mechanism of Action NR2B N-Methyl-D-Aspartate antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Major depressive disorder

Most Recent Events

  • 14 May 2014 Janssen plans to continue development of EVT 101 for Major depressive disorder
  • 17 Dec 2012 EVT 101 (including other NR2B selective NMDA antagonists) licensed to Janssen Pharmaceuticals worldwide for Major depressive disorder
  • 08 Sep 2011 Evotec Neurosciences GmbH terminates phase II trial in treatment-resistant Major depressive disorder in USA (NCT01128452)
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