Drug Profile


Alternative Names: 751689; Ronacaleret Hydrochloride; SB-751,689; SB-751689-A

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator NPS Pharmaceuticals
  • Developer GlaxoSmithKline
  • Class Osteoporosis therapies; Propionic acids; Small molecules
  • Mechanism of Action Calcium-sensing receptor antagonists; Osteogenesis stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Fracture; Postmenopausal osteoporosis; Stem cell mobilisation

Most Recent Events

  • 15 Dec 2016 Biomarkers information updated
  • 01 Mar 2016 Discontinued - Phase-I for Postmenopausal osteoporosis (In volunteers) in USA (PO) (NCT00651534)
  • 21 Jul 2015 Discontinued - Phase-II for Stem cell mobilisation in USA (PO)
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