Drug Profile


Alternative Names: Efficib; Januet; Janumet; Metformin/sitagliptin; MK-0431A; ONO 5434A; ONO-5435A; Ristfor; Sitagliptin and metformin HCl; Velmetia

Latest Information Update: 22 Mar 2017

Price : $50

At a glance

  • Originator Merck & Co
  • Class Antihyperglycaemics; Biguanides; Insulin sensitisers; Pyrazines; Small molecules; Triazoles
  • Mechanism of Action AMP activated protein kinase stimulants; CD26 antigen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Type 2 diabetes mellitus

Most Recent Events

  • 28 Feb 2017 Merck has patent protection for sitagliptin/metformin in Europe (Merck Annual report 2016)
  • 25 Sep 2015 Merck has patent protection for sitagliptin/metformin in USA (Merck 10-K, September 2015)
  • 03 Jun 2015 Launched for Type-2 diabetes mellitus in Vietnam, Indonesia, China, Taiwan, South Korea, Panama, Peru, Serbia, Kazakhstan, Egypt, Malta, Finland, Iceland, Lithuania, Latvia and Croatia (PO) before June 2015
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