Drug Profile


Alternative Names: Efficib; Januet; Janumet; Metformin/sitagliptin; MK-0431A; ONO 5434A; ONO-5435A; Ristfor; Sitagliptin and metformin HCl; Velmetia

Latest Information Update: 04 Dec 2015

Price : $50

At a glance

  • Originator Merck & Co
  • Class Antihyperglycaemics; Biguanides; Insulin sensitisers; Pyrazines; Small molecules; Triazoles
  • Mechanism of Action AMP activated protein kinase stimulants; CD26 antigen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Type 2 diabetes mellitus

Most Recent Events

  • 25 Sep 2015 Merck has patent protection for sitagliptin/metformin in USA (Merck 10-K, September 2015)
  • 03 Jun 2015 Launched for Type-2 diabetes mellitus in Vietnam, Indonesia, China, Taiwan, South Korea, Panama, Peru, Serbia, Kazakhstan, Egypt, Malta, Finland, Iceland, Lithuania, Latvia and Croatia (PO) before June 2015
  • 05 May 2015 Phase-III clinical trials in Type-2 diabetes mellitus (In adolescents, In children) in United Arab Emirates, Thailand, Sri Lanka, Saudi Arabia, Russia, Romania, New Zealand, Mexico, Malaysia, Israel, Guatemala, Dominican Republic, Costa Rica, Colombia, Chile, Canada and Argentina (PO)
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