Drug Profile


Alternative Names: AIN-457; Cosentyx; Human anti-interleukin-17A monoclonal antibody; KB-03303A; NVP-AIN 457; Scapho

Latest Information Update: 18 Apr 2017

Price : $50

At a glance

  • Originator Alcon; Novartis
  • Developer Icahn School of Medicine at Mount Sinai; Novartis
  • Class Anti-inflammatories; Monoclonal antibodies
  • Mechanism of Action Interleukin-17 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Plaque psoriasis; Psoriatic arthritis
  • Registered Ankylosing spondylitis; Pustular psoriasis
  • Phase III Psoriasis; Rheumatoid arthritis
  • Phase II Alopecia areata; Atopic dermatitis
  • Discontinued Asthma; Crohn's disease; Dry eyes; Multiple sclerosis; Polymyalgia rheumatica; Type 1 diabetes mellitus; Uveitis

Most Recent Events

  • 21 Mar 2017 Efficacy data from the phase III A2302E1 extension trial in Psoriasis released by Novartis
  • 06 Mar 2017 Efficacy data from pooled analysis of phase III trials presented at 2017 American Academy of Dermatology (AAD) Annual Meeting
  • 01 Feb 2017 Phase-III clinical trials in Plaque psoriasis in Hungary (SC) (EudraCT2016-000524-25)
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