Cytarabine/daunorubicin liposomal

Drug Profile

Cytarabine/daunorubicin liposomal

Alternative Names: CPX-351; Cytarabine:daunorubicin - Jazz Pharmaceuticals; Cytarabine:daunorubicin liposome injection - Jazz Pharmaceuticals; Daunorubicin/cytarabine; NS 87; VYXEOS

Latest Information Update: 04 Sep 2017

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At a glance

  • Originator Celator Pharmaceuticals
  • Developer Cardiff University; Celator Pharmaceuticals; Cincinnati Childrens Hospital Medical Center; Fred Hutchinson Cancer Research Center; Jazz Pharmaceuticals plc; National Cancer Institute (USA); Stanford University; The Leukemia & Lymphoma Society; University of Texas M. D. Anderson Cancer Center
  • Class Anthracyclines; Antineoplastics; Arabinonucleosides; Cytostatic antibiotics; Daunorubicins; Nucleosides; Small molecules
  • Mechanism of Action Antimetabolites; DNA intercalators; DNA synthesis inhibitors; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity No

Highest Development Phases

  • Marketed Acute myeloid leukaemia
  • Phase III Myelodysplastic syndromes
  • Phase II Acute lymphoblastic leukaemia
  • Phase I Lymphoma

Most Recent Events

  • 04 Sep 2017 Launched for Acute myeloid leukaemia (First-line therapy, Newly disgnosed) in USA (IV) (Jazz Pharmaceuticals website, September 2017)
  • 17 Aug 2017 Chemical structure information added
  • 03 Aug 2017 Cytarabine/daunorubicin liposomal under the brand name Vyxeos™ will be commercially available in August 2017
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