Cytarabine/daunorubicin liposomal

Drug Profile

Cytarabine/daunorubicin liposomal

Alternative Names: CPX-351; Cytarabine:daunorubicin - Celator; Cytarabine:daunorubicin liposome injection - Celator; Daunorubicin/cytarabine; VYXEOS

Latest Information Update: 12 Apr 2017

Price : $50

At a glance

  • Originator Celator Pharmaceuticals
  • Developer Cardiff University; Celator Pharmaceuticals; Cincinnati Childrens Hospital Medical Center; Fred Hutchinson Cancer Research Center; National Cancer Institute (USA); Stanford University; The Leukemia & Lymphoma Society; University of Texas M. D. Anderson Cancer Center
  • Class Anthracyclines; Antineoplastics; Arabinonucleosides; Cytostatic antibiotics; Daunorubicins; Nucleosides; Small molecules
  • Mechanism of Action Antimetabolites; DNA intercalators; DNA synthesis inhibitors; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Preregistration Acute myeloid leukaemia
  • Phase III Myelodysplastic syndromes
  • Phase II Acute lymphoblastic leukaemia
  • Phase I Lymphoma

Most Recent Events

  • 31 Mar 2017 Jazz Pharmaceuticals completes rolling submission of an NDA for cytarabine/daunorubicin liposomal for Acute myeloid leukaemia
  • 30 Mar 2017 Jazz Pharmaceuticals and Nippon Shinyaku agree to co-promote and co-develop cytarabine/daunorubicin liposomal in Japan for Acute myeloid leukaemia
  • 03 Dec 2016 Updated exploratory subgroup analysis data from a phase III trial in Acute myeloid leukaemia (First-line therapy, In the elderly) presented at the 58th American Society of Hematology Annual Meeting and Exposition (ASH-2016)
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