Cytarabine/daunorubicin liposomal

Drug Profile

Cytarabine/daunorubicin liposomal

Alternative Names: CPX-351; Cytarabine:daunorubicin - Celator; Cytarabine:daunorubicin liposome injection - Celator; Daunorubicin/cytarabine; NS 87; VYXEOS

Latest Information Update: 15 Jul 2017

Price : $50

At a glance

  • Originator Celator Pharmaceuticals
  • Developer Cardiff University; Celator Pharmaceuticals; Cincinnati Childrens Hospital Medical Center; Fred Hutchinson Cancer Research Center; National Cancer Institute (USA); Stanford University; The Leukemia & Lymphoma Society; University of Texas M. D. Anderson Cancer Center
  • Class Anthracyclines; Antineoplastics; Arabinonucleosides; Cytostatic antibiotics; Daunorubicins; Nucleosides; Small molecules
  • Mechanism of Action Antimetabolites; DNA intercalators; DNA synthesis inhibitors; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Preregistration Acute myeloid leukaemia
  • Phase III Myelodysplastic syndromes
  • Phase II Acute lymphoblastic leukaemia
  • Phase I Lymphoma

Most Recent Events

  • 02 Jun 2017 Efficacy and adverse events data from a phase III trial in Acute myeloid leukaemia (First-line therapy, In the elderly) presented at the 53rd Annual Meeting of the American Society of Clinical Oncology (ASCO-2017)(3252416; 3252422)
  • 31 May 2017 The US FDA accepts NDA for cytarabine/ daunorubicin for Acute myeloid leukaemia for review
  • 01 Apr 2017 Pharmacodynamics data from a preclinical trial in Acute myeloid leukaemia presented at the 108th annual meeting of the American Association for Cancer Research (AACR-2017)
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