Drug Profile


Alternative Names: ASONEP; iSONEP; LT-1009; Sonepcizumab/LT1009; Sphingomab™

Latest Information Update: 30 Jun 2017

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At a glance

  • Originator Lpath
  • Developer Lpath; Pfizer
  • Class Antineoplastics; Eye disorder therapies; Monoclonal antibodies
  • Mechanism of Action Angiogenesis inhibitors; Sphingosine 1 phosphate receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Wet age-related macular degeneration
  • Preclinical Diabetic retinopathy; Eye disorders; Inflammation; Multiple sclerosis
  • Discontinued Heart failure; Renal cell carcinoma

Most Recent Events

  • 15 Jun 2017 MRC Technology is now called LifeArc
  • 16 Dec 2016 Biomarkers information updated
  • 22 Mar 2016 Sonepcizumab is no longer licensed to Pfizer in USA(Lpath, Form 10-K, March 2016)
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