Research programme: neurodegenerative disorders therapeutics - CombinatoRx

Drug Profile

Research programme: neurodegenerative disorders therapeutics - CombinatoRx

Latest Information Update: 22 Sep 2010

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At a glance

  • Originator CHDI; Zalicus
  • Developer CHDI; CombinatoRx; Zalicus
  • Class
  • Mechanism of Action Survival of motor neuron 1 protein stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Huntington's disease; Spinal muscular atrophy

Most Recent Events

  • 31 Dec 2007 Discontinued - Preclinical for Spinal muscular atrophy in USA (unspecified route)
  • 21 May 2007 Lead identification is ongoing
  • 31 Aug 2005 Preclinical trials in Huntington's disease in USA (unspecified route)
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