Irinotecan-eluting beads - Biocompatibles

Drug Profile

Irinotecan-eluting beads - Biocompatibles

Alternative Names: CM-BC2; DEBIRI; Irinotecan bead; Irinotecan-loaded DC Bead LUMI™; Irinotecan-loaded DC BeadM1™; Irinotecan-loaded DC Bead™; PARAGON Bead

Latest Information Update: 25 Apr 2017

Price : $50

At a glance

  • Originator Biocompatibles International
  • Developer Biocompatibles International; BTG; Singapore General Hospital
  • Class Alkaloids; Antineoplastics; Camptothecins; Small molecules
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma
  • New Molecular Entity No

Highest Development Phases

  • Marketed Colorectal cancer; Liver metastases
  • Phase II Cholangiocarcinoma
  • Phase I/II Glioma

Most Recent Events

  • 29 Jul 2016 BTG International terminates a phase I clinical trials in Glioma (Recurrent, Adjuvant therapy) in United Kingdom (unspecified route) (NCT02433392)
  • 13 Aug 2015 Phase-II development for Liver metastases is ongoing in USA
  • 01 Dec 2014 Universitaire Ziekenhuizen Leuven and Biocompatibles terminate a feasibility trial for Liver metastases (first-line combination therapy, unresectable disease) in Belgium prior to initiation (NCT01631539)
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